The phase-III human clinical trial began at the Sassoon General Hospital in Pune on September 17. King Edward Memorial (KEM) Hospital in Mumbai on September 23 began the phase II and III trials of the coronavirus vaccine.

Some participants in the trials for the coronavirus vaccine have also received their second doses and have not reported any adverse side-effects.

However, some did develop a fever after the dose of the coronavirus vaccine, but top scientists said that those are mild reactions and should not be worried about.

Some investigators also said that developing a fever is considered a common and mild side-effect of vaccines.

In September, Aztra Zeneca Plc said it has paused a late-stage trial of one of the leading coronavirus vaccine candidates after an unexplained illness in a study participant. After reviews the safety of the vaccine and its procedures, the human trials were resumed.

The Pune-based Serum Institute of India (SII) has partnered with British-Swedish pharma company AstraZeneca for manufacturing the coronavirus vaccine candidate, being developed by the University of Oxford, UK.

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The Union Ministry of Health & Family Welfare (MoH&FW) officials are maintaining that the COVID-19 case fatality rate (CFR) is below 2% and are trying to bring it down to under 1%.

Trials for the Oxford University’s vaccine, developed in collaboration with AstraZeneca, will begin in India on Wednesday. Six volunteers will be administered doses at Pune’s Bharati Vidyapeeth medical college and hospital. This is phase-2 of the trial, as it is not mandatory to conduct phase-1 trials in India, where the vaccine’s safety is assessed.

The Center is in talks with Russia over its vaccine for Covid-19, called Sputnik-V. “As far as Sputnik-V vaccine is concerned, India and Russia are in communication. Some initial information has been shared,” Health Secretary Rajesh Bhushan said at a press conference.

Fresh guidelines for Unlock 4.0 are expected to be announced in the coming days. The Metro service in Delhi NCR, suspended since March 22 due to the pandemic, is likely to resume in September.

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